Pinchas Cohen Selected Research

Insulin-Like Growth Factor Binding Protein 3

2/2013	IGFBP-3 nuclear localization predicts human prostate cancer recurrence.
8/2011	IGFBP-3 is a metastasis suppression gene in prostate cancer.
10/2009	Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation.
2/2007	Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo.
1/2007	Spinal bone mineral density, IGF-1 and IGFBP-3 in children with cerebral palsy.
11/2006	Phosphorylation by DNA-dependent protein kinase is critical for apoptosis induction by insulin-like growth factor binding protein-3.
9/2006	Insulin-like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma.
1/2006	Identification of insulin-like growth factor binding protein-3 as a farnesyl transferase inhibitor SCH66336-induced negative regulator of angiogenesis in head and neck squamous cell carcinoma.
7/2005	Combination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo.
6/2005	p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.

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Pinchas Cohen Research Topics

Disease

53	Neoplasms (Cancer) 01/2022 - 06/2002
41	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 08/2002
10	Insulin Resistance 01/2021 - 10/2002
9	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 10/2003
6	Neoplasm Metastasis (Metastasis) 03/2021 - 09/2006
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 07/2005
5	Type 2 Diabetes Mellitus (MODY) 01/2022 - 03/2004
5	Inflammation (Inflammations) 01/2022 - 09/2012
5	Cognitive Dysfunction 01/2020 - 03/2008
5	Body Weight (Weight, Body) 01/2018 - 03/2004
5	Starvation 10/2016 - 08/2002
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 03/2016
4	Macular Degeneration (Age-Related Maculopathy) 01/2022 - 01/2017
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 11/2005
4	Obesity 01/2019 - 03/2004
4	Carcinogenesis 12/2018 - 09/2002
4	Adenocarcinoma 10/2010 - 11/2007
3	Cerebral Palsy (Spastic Diplegia) 03/2007 - 08/2004
2	Squamous Cell Carcinoma of Head and Neck 01/2019 - 01/2006
2	Overweight 01/2018 - 05/2013
2	Weight Loss (Weight Reduction) 01/2018 - 03/2004
2	Weight Gain 11/2017 - 04/2014
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2017 - 04/2015
2	Male Infertility (Male Sterility) 04/2015 - 01/2010
2	Melanoma (Melanoma, Malignant) 03/2014 - 02/2010
2	Hypoxia (Hypoxemia) 02/2013 - 06/2005
2	Atherosclerosis 09/2012 - 11/2011
2	Prostatic Intraepithelial Neoplasia 04/2008 - 11/2007
2	Hypogonadism (Hypergonadotropic Hypogonadism) 03/2008 - 03/2004
2	Metabolic Bone Diseases (Osteopenia) 03/2007 - 01/2007
2	Ewing Sarcoma (Sarcoma, Ewing) 09/2006 - 08/2004
2	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 08/2006 - 07/2005
2	Chronic Kidney Failure (Chronic Renal Failure) 03/2005 - 01/2004
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022
1	Hyperthermia 11/2021
1	Adenocarcinoma of Lung 03/2021
1	Multiple Abnormalities 03/2021

Drug/Important Bio-Agent (IBA)

26	Insulin-Like Growth Factor I (IGF-1)IBA 02/2016 - 08/2002
21	Insulin-Like PeptidesIBA 01/2019 - 06/2002
20	Peptides (Polypeptides)IBA 01/2022 - 10/2003
19	humaninIBA 01/2022 - 08/2006
18	Insulin-Like Growth Factor Binding Protein 3IBA 02/2013 - 06/2002
14	Insulin (Novolin)FDA Link 01/2019 - 07/2003
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2004
7	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2022 - 08/2006
7	Insulin-Like Growth Factor Binding Protein 1IBA 01/2018 - 10/2002
6	Glucose (Dextrose)FDA LinkGeneric 11/2017 - 10/2002
6	Insulin-Like Growth Factor Binding ProteinsIBA 08/2011 - 09/2002
6	Growth Hormone (Somatotropin)IBA 03/2008 - 09/2002
5	Mitochondrial DNA (mtDNA)IBA 01/2022 - 11/2017
5	Fish OilsIBA 01/2019 - 08/2006
5	Biomarkers (Surrogate Marker)IBA 01/2018 - 03/2007
5	AndrogensIBA 10/2016 - 05/2003
5	Prostate-Specific Antigen (Semenogelase)IBA 08/2006 - 05/2003
4	TransferasesIBA 01/2019 - 07/2005
4	CytokinesIBA 10/2016 - 06/2005
4	Dietary Fats (Dietary Fat)IBA 07/2012 - 07/2003
4	Hormones (Hormone)IBA 01/2010 - 09/2005
4	Insulin-Like Growth Factor Binding Protein 2IBA 02/2009 - 05/2003
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 08/2006
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 08/2006
3	CholesterolIBA 01/2018 - 11/2011
3	ganitumabIBA 04/2014 - 07/2012
3	IGF Type 1 Receptor (IGF 1 Receptor)IBA 07/2013 - 02/2010
3	Messenger RNA (mRNA)IBA 02/2010 - 07/2003
2	AcidsIBA 01/2022 - 11/2010
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2022
2	Biological ProductsIBA 01/2020 - 10/2018
2	Corn Oil (Oil, Corn)IBA 01/2019 - 10/2016
2	LeptinIBA 01/2018 - 03/2004
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2015 - 02/2010
2	Amino Acids FDA Link 04/2013 - 08/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2012 - 02/2007
2	Apolipoproteins E (ApoE)IBA 09/2012 - 11/2011
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2011 - 08/2006
2	Tumor Biomarkers (Tumor Markers)IBA 12/2009 - 08/2006
2	CarbohydratesIBA 06/2009 - 01/2008
2	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 08/2007 - 07/2004
2	DNA (Deoxyribonucleic Acid)IBA 11/2006 - 06/2005
2	LigandsIBA 07/2005 - 07/2003
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 06/2005 - 07/2004
2	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2004 - 01/2003
2	Telomerase (Telomerase Reverse Transcriptase)IBA 07/2003 - 05/2003
2	EnzymesIBA 07/2003 - 05/2003
1	P-SelectinIBA 01/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	E-SelectinIBA 01/2022
1	Interleukin-13IBA 01/2022
1	MicropeptidesIBA 01/2022
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022
1	LuciferasesIBA 01/2022
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2022
1	ElementsIBA 01/2022
1	Adenosine Triphosphate (ATP)IBA 03/2021

Therapy/Procedure

15	Therapeutics 01/2022 - 05/2003
7	Fat-Restricted Diet (Diet, Fat Restricted) 07/2012 - 12/2002
5	Drug Therapy (Chemotherapy) 10/2016 - 12/2009
3	Caloric Restriction 01/2018 - 07/2010
3	Prostatectomy (Retropubic Prostatectomy) 01/2018 - 05/2013